Health Data From Humans, Not AI
$650/yr
$54/month, charged annually
Unlock a greater understanding of your health with Preamble's comprehensive biomarker testing. We measure up to 175 key indicators to give you a complete picture of how your body is performing.
Plus, you'll meet with a real Preamble provider to review your results, so you won't have to interpret an impersonal AI report on your own.
Optional add-on: HRT, TRT, and GLP-1 medication support — $100/month plus medication costs.
What's included
Lab work for up to 175 biomarkers
Take a deep dive into your health with measurements not typically included in a standard physical, including blood sugar and insulin resistance, cardiovascular risk, electrolytes, hormones, kidney and liver function, inflammation, and thyroid. Includes 1 initial draw and 1 mid-year draw.
1:1 consultation with a REAL person, not AI
After your initial annual draw, you'll have a 20-minute consultation with a Preamble provider who will review your results, answer your questions, and give you actionable insights based on your personal data.
Option to add HRT and GLP-1 support
Add our medication support program for Hormone Replacement Therapy (HRT), Testosterone Replacement Therapy (TRT), or weight loss GLP-1 medications.*
*Additional fee. Medications not included.
One simple process
Schedule your test
Book an appointment to visit a lab near you or schedule an in-home visit.
Get your blood draw
A quick blood draw and urine sample will give us actionable insights into your health.
Meet with the Provider
Meet in-person or virtually to review the results of your initial draw and discuss an action plan.
See what your primary care physician doesn't measure
We go far beyond the standard physical, testing up to 175 biomarkers across 20 categories — giving you a complete picture of how your body is actually functioning.
Heart / Cardiovascular Health 12
Apolipoprotein B
Counts the number of cholesterol-carrying particles for artery risk assessment.
Lipoprotein (a)
Inherited particle that independently raises cardiovascular disease risk.
Total Cholesterol
Sum of all cholesterol types; blunt screening tool.
HDL Cholesterol
Helps transport cholesterol back to the liver for recycling.
Triglycerides
Blood fats that rise with refined carbs and alcohol; elevation can increase risk.
LDL Cholesterol
Cholesterol cargo within LDL particles; useful but less precise than ApoB.
Cholesterol/HDLC Ratio
Traditional metric for gauging overall heart risk.
Non-HDL Cholesterol
Captures cholesterol in all "bad" particles when ApoB is unavailable.
Myeloperoxidase*
White blood cell enzyme linked to oxidative stress in arteries.
Trimethylamine N-oxide
Gut metabolite linked to cardiovascular and kidney risk.
OxLDL*
Oxidized LDL more likely to irritate artery walls.
Lp-PLA2 Activity*
Enzyme tied to artery inflammation and plaque activity.
Thyroid 7
TSH
Pituitary control signal regulating thyroid function intensity.
Free T3
Active thyroid hormone your cells actually use for metabolism.
Free T4
Main hormone released by thyroid; converted to T3 as needed.
Reverse T3*
Inactive form rising during illness, stress, or calorie deficiency.
TPO Antibodies*
Indicates immune system targeting thyroid tissue.
Thyroglobulin Antibodies*
Detects immune damage to thyroid cells.
Iodine*
Essential building block for thyroid hormone production.
Autoimmunity 2
ANA (Antinuclear Antibodies)*
Antibodies targeting cell nuclei, often seen in autoimmune diseases.
Rheumatoid Factor*
Antibody potentially indicating rheumatoid arthritis or autoimmune activity.
Pancreas 3
Amylase*
Detects salivary disease, pancreatitis, celiac disease, IBD, or tumors.
Lipase*
Identifies pancreatic inflammation and biliary system conditions.
CA 19-9*
Tumor marker for monitoring pancreatic or biliary conditions.
Gut Health 1
Jona Test*
Detailed gut microbiome analysis with personalized insights.
Dementia 1
Cardio IQ APOE Genotype*
Tests gene type influencing Alzheimer's risk.
Genetic 2
MTHFR*
Gene affecting folate and homocysteine processing; variants reduce enzyme efficiency.
Invitae Comprehensive Genetic Risk Panel*
Assesses individuals for hereditary conditions including cancers, cardiovascular and metabolic diseases — 163 genes analyzed.
Metabolic Health 18
Hemoglobin A1c
Reflects average blood sugar over approximately 3 months.
Insulin
Shows metabolic effort maintaining fasting blood sugar; early resistance indicator.
Uric Acid
Breakdown product; elevated levels raise blood pressure and vessel irritation.
Homocysteine
Sulfur-based amino acid; elevated levels irritate blood vessel linings.
Leptin*
Fat cell hormone signaling fullness; high levels indicate potential resistance.
HOMA-IR Score
Calculated score estimating insulin resistance.
Glucose
Single morning fasting blood sugar measurement.
eGFR
Kidney filtration efficiency estimate; higher indicates better function.
Bun/Creatinine Ratio
Interprets kidney and hydration status.
Sodium
Main blood salt reflecting water balance.
Potassium
Mineral maintaining nerve and heart rhythm within tight ranges.
Chloride
Ion supporting acid-base balance with sodium.
Carbon Dioxide
Reflects bicarbonate, the blood's acid buffer system.
Calcium
Mineral essential for bones, nerves, and muscles.
Globulin
Blood proteins including antibodies and carrier proteins.
Albumin/Globulin Ratio
Compares liver-made albumin to immune-related globulins.
Bilirubin, Total
Red cell breakdown product processed by the liver.
Alkaline Phosphatase
Enzyme from bile ducts and bone tissue.
Nutrients & Minerals 18
Selenium*
Trace mineral crucial for thyroid hormone activation and antioxidant defense.
Methylmalonic Acid*
Sensitive B12 status marker; elevated indicates functional deficiency.
Magnesium, RBC*
Red cell magnesium reflecting body stores more accurately than serum.
Vitamin B12*
Supports nerves, brain, and red blood cells.
Folate*
Essential for DNA repair and blood cell production.
Zinc*
Mineral supporting immune function, wound healing, and hormone balance.
Copper*
Works with iron for red blood cell and energy production.
OmegaCheck (EPA+DPA+DHA)
Red blood cell omega-3 profile reflecting the last 2–3 months.
EPA
Omega-3 that helps cool inflammation and lower triglycerides.
DPA
Intermediate omega-3 supporting anti-inflammatory balance and cell membrane flexibility.
DHA
Omega-3 supporting brain, eye, and heart cell membranes.
Omega-3 Total
Sum of all omega-3 fats indicating anti-inflammatory status.
Omega-6 Total
Sum of omega-6 fats used for cell structure.
Omega-6/Omega-3 Ratio
Balance between inflammatory and anti-inflammatory fats.
Arachidonic Acid/EPA Ratio
Reflects inflammatory balance between two key fatty acids.
Arachidonic Acid
Omega-6 fat needed for repair and signaling.
Linoleic Acid
Common omega-6 fat found in vegetable oils.
Vitamin D
Storage form supporting bone, muscle, and immune health.
Inflammation 2
High-Sensitivity C-Reactive Protein
Sensitive whole-body inflammation marker; lower is preferred.
Ferritin
Iron storage indicator; elevation suggests inflammation or iron overload.
Liver 5
GGT
Liver enzyme rising with hepatic injury.
Albumin
Primary liver-produced protein maintaining vessel fluid and hormone transport.
AST
Liver enzyme also rising with hard workouts or muscle injury.
ALT
Liver enzyme that rises when the liver is irritated or fatty.
Total Protein
Sum of albumin and globulins representing nutrition and immunity proteins.
Kidneys 28
Cystatin C
Kidney function marker less affected by muscle mass than creatinine.
Creatinine
Muscle-waste marker filtered by kidneys; higher indicates lower filtration.
BUN (Blood Urea Nitrogen)
Protein-waste marker rising with dehydration.
Gravity (urine)
Measures urine concentration; high indicates dehydration.
pH (urine)
Reflects acidity or alkalinity level.
Glucose (urine)
Detects sugar spillover from elevated blood sugar or diabetes.
Bilirubin (urine)
Appears when liver or bile system is stressed.
Ketones (urine)
Seen in fasting, low-carb diets, or uncontrolled diabetes.
Occult Blood (urine)
Detects non-visible blood traces from infection, stones, or exercise.
Protein (urine)
Checks for albumin; persistent elevation may signal kidney stress.
Nitrite (urine)
Indicates nitrite-producing bacteria; often present in urinary tract infections.
Leukocyte Esterase (urine)
Suggests white blood cells; common UTI indicator.
WBC (urine)
Microscopic white blood cells; infection or inflammation marker.
RBC (urine)
Red blood cells suggesting irritation, stones, or infection.
Squamous Epithelial Cells (urine)
Urinary tract surface cells; excess may indicate contamination.
Transitional Epithelial Cells (urine)
Bladder lining cells; high numbers reflect irritation or injury.
Renal Epithelial Cells (urine)
Kidney tubule cells; presence suggests possible kidney injury.
Bacteria (urine)
Indicates bacterial presence.
Calcium Oxalate Crystals (urine)
Common crystals potentially increasing with dehydration.
Triple Phosphate Crystals (urine)
Appear in alkaline urine, often associated with infection.
Uric Acid Crystals (urine)
Form in acidic urine; linked to gout or kidney stones.
Amorphous Sediment (urine)
Unstructured crystal deposits.
Crystals (urine)
General solid particle category.
Hyaline Cast (urine)
Tube-shaped protein molds from kidney tubules.
Granular Cast (urine)
Casts containing cell debris.
Casts (urine)
Tubular structures; type determines significance.
Yeast (urine)
Presence suggests possible fungal infection.
Albumin, Urine
Detects small protein amounts in urine.
Women's Health 10
Estradiol
Main estrogen supporting mood, bone, heart, and healthy cycles.
FSH (Follicle-Stimulating Hormone)
Brain signal helping ovaries produce eggs.
LH (Luteinizing Hormone)
Brain signal triggering ovulation in women.
Progesterone
Hormone rising post-ovulation; supports uterine lining and balances estrogen.
AMH*
Ovarian follicle marker reflecting egg reserve and fertility potential.
DHEA Sulfate
Steady adrenal androgen marker influencing testosterone and estrogen.
Prolactin*
Pituitary hormone supporting milk production; elevation disrupts cycles.
Sex Hormone Binding Globulin
Carrier protein regulating hormone availability.
Free Testosterone
Unbound active testosterone directly measured and more accurate.
Total Testosterone
Overall circulating testosterone affecting energy, libido, and mood.
Men's Health 10
Sex Hormone Binding Globulin
Carrier protein regulating hormone availability.
Free Testosterone
Unbound active testosterone directly measured and more accurate.
Total Testosterone
Overall circulating testosterone affecting energy, libido, and mood.
Estradiol
Main estrogen supporting mood, bone, and heart function.
FSH (Follicle-Stimulating Hormone)
Brain signal helping testes produce sperm.
LH (Luteinizing Hormone)
Brain signal telling testes to make testosterone.
DHEA Sulfate
Steady adrenal androgen marker influencing testosterone and estrogen.
PSA Total
Prostate protein used for screening and monitoring over time.
PSA Free*
Unbound prostate antigen fraction; ratio distinguishes benign from higher-risk changes.
Prolactin*
Pituitary hormone; elevation disrupts testosterone balance.
Blood Health & Anemia 37
White Blood Cell Count
Infection-fighting cells; levels vary with illness and inflammation.
Red Blood Cell Count
Number of red cells; useful alongside hemoglobin and hematocrit.
Hemoglobin
Oxygen-carrying protein in red cells; screens for anemia.
Hematocrit
Percentage of blood that's red cells; screens for anemia or high counts.
MCV
Average red cell size helping classify anemia type.
MCH
Average hemoglobin per red cell.
MCHC
Hemoglobin concentration inside red cells; adds anemia classification context.
RDW
Shows variation in red cell sizes.
Platelet Count
Platelets help your blood clot; too few raises bleeding risk.
MPV
Average platelet size indicator.
Neutrophils
Neutrophil percentage within total white count.
Absolute Neutrophils
Core infection-fighting cells; high in bacterial infection.
Lymphocytes
White blood cells driving immune memory and viral defense.
Absolute Lymphocytes
White cell subtype counts reflecting infection or inflammation type.
Monocytes
Long-lived cells clearing infection and supporting healing.
Absolute Monocytes
Measures cleanup and infection-fighting monocytes.
Eosinophils
Eosinophil percentage within total white count.
Absolute Eosinophils
White cell counts reflecting infection, allergy, or inflammation.
Basophils
Basophil percentage within total white count.
Absolute Basophils
White cell subtype counts reflecting infection or inflammation.
Band Neutrophils
Immature neutrophil forms released during infection or inflammation.
Absolute Band Neutrophils
Early white blood cells released during infection or inflammation.
Metamyelocytes
Immature white cell developmental stages.
Absolute Metamyelocytes
Very immature white blood cells.
Myelocytes
Immature white cell developmental stages.
Absolute Myelocytes
Early-stage white blood cell form.
Promyelocytes
Immature white cell developmental stages.
Absolute Promyelocytes
Even more immature precursor cells.
Reactive Lymphocytes
Activated lymphocytes in viral infections or immune reactions.
Blasts
Early immature marrow cells; normally absent.
Absolute Blasts
Immature precursor cells normally absent from circulation.
Nucleated RBC
Immature red cells.
Absolute Nucleated RBC
Red cell precursors typically remaining in bone marrow.
Iron, Total*
Total circulating iron bound to transport proteins.
Iron, Binding Capacity*
Blood's ability to carry iron measurement.
Iron % Saturation*
Percentage of binding sites filled with iron.
Blood Type*
Basic blood type (A, B, AB, or O); important for transfusions.
Infectious Disease 1
Lyme Disease*
Tests for antibodies that confirm exposure or infection from tick-borne bacteria.
Cancer Detection 1
Galleri by Grail*
Multi-cancer early detection test screening for many deadly cancers before symptoms appear.
Sexual Health 8
Trichomonas*
Detects Trichomonas vaginalis parasitic infection.
Chlamydia / N. Gonorrhoeae*
Detects two bacterial sexually transmitted infections.
HSV 1/2 IgG, Type Specific Antibody*
Identifies herpes simplex virus 1 and 2 antibodies.
HIV 1/2 Antigen/Antibody, Fourth Generation with Reflex*
High-sensitivity HIV screening.
RPR (DX) with Reflex Titer and Confirmatory Testing*
Syphilis screening with confirmation.
Syphilis*
Screens for Treponema pallidum antibodies.
Hepatitis B*
Detects viral antigens or antibodies for current or past infection.
Hepatitis C*
Screens for antibodies or viral RNA detecting hepatitis C.
Toxins & Heavy Metals 5
Mercury, Blood*
Heavy metal from fish, occupations, or dental materials; reflects recent exposure.
Lead (venous)*
Toxic metal with no safe level; from old paint, plumbing, or hobbies.
Arsenic, Blood*
Exposure from well water, rice, industry, or seafood sources.
Aluminum, Blood*
Tests exposure from cookware, deodorants, and medications.
BPA Exposure*
Chemical in plastics and food linings; potential hormone disruptor assessment.
Stress & Aging 1
Cortisol
Main stress hormone following daily rhythm; regulates energy, blood sugar, and inflammation.
Get Clear Insights Into Your Health for only $650
HSA/FSA eligible · No insurance accepted
Measure up to 175 biomarkers
Take a deep-dive into your health with measurements not typically included in a standard physical.
Meet with a REAL person, not AI
We review your results, answer your questions, and give you actionable insights based on your personal data.
Add HRT and GLP-1 support
Support for Hormone Replacement Therapy (HRT), Testosterone Replacement Therapy (TRT), and weight loss GLP-1 medications.
*Additional fee. Medications not included.
Questions about the Preamble Core Membership
Everything you need to know about Preamble — from how to get started to pricing, insurance, and what to expect.
What does the Preamble Core Membership include?
- Measure 160+ biomarkers over the course of a year — 1 initial draw and 1 mid-year draw
- Member-only rates on repeat testing and other blood tests not covered by Core Membership
- Annual review of your tests with a Preamble provider — not AI
- Access to support for Hormone Replacement Therapy (HRT), Testosterone Replacement Therapy (TRT) and weight loss GLP-1 medications*
*HRT and GLP-1 support is an additional $100/month plus the cost of medications. Includes all practitioner visits and up to 2 additional lab visits/draws related to medication support.
Who would benefit from the Preamble Core Membership?
Anyone starting on a health journey, seeking foundational health benchmarks, or looking for basic HRT, TRT, or GLP-1 support.
Does Preamble offer medication support for Hormone Replacement Therapy (HRT) or Testosterone Replacement Therapy (TRT)?
Yes, we do! You can add medication support to your Core Membership for an additional $100/month, plus the cost of medications. Includes all practitioner visits and up to 2 additional lab visits/draws related to medication support.
Does Preamble offer medication support for GLP-1s?
Yes, we do! You can add medication support to your Core Membership for an additional $100/month, plus the cost of medications. Includes all practitioner visits and up to 2 additional lab visits/draws related to medication support.
Is the Membership covered by insurance?
No, but all Preamble services and memberships are HSA/FSA eligible.
Where is Preamble located?
How do I get started?
Click the Start Testing button below to create an account and book an appointment.
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